Ampicillin Sodium is a broad-spectrum, beta-lactam penicillin-class antibiotic, used parenterally to treat various bacterial infections. It inhibits bacterial cell wall synthesis, making it effective against both Gram-positive and some Gram-negative organisms.
✅ Approved & Common Indications
🌿 Respiratory Tract Infections
- Indicated for upper and lower respiratory tract infections, such as:
📌 Pneumonia
📌 Bronchitis
📌 Pharyngitis or tonsillitis (caused by susceptible strains)
🌿 Genitourinary Tract Infections
- Effective in treating urinary tract infections (UTIs) and gonorrhea, caused by susceptible bacteria including E. coli, Proteus mirabilis, and Neisseria gonorrhoeae.
🌿 Gastrointestinal Infections
- Used in the treatment of enteric infections, such as salmonellosis, shigellosis, and Listeria monocytogenes infections.
🌿 Meningitis
- Indicated for bacterial meningitis, especially caused by Listeria monocytogenes in neonates and immunocompromised individuals (often in combination with other agents like gentamicin).
🌿 Septicemia and Endocarditis
- Used in treating septicemia and bacterial endocarditis, particularly in combination therapy with aminoglycosides for synergistic effects.
🌿 Skin and Soft Tissue Infections
- Indicated for infections like cellulitis, erysipelas, and wound infections caused by susceptible organisms.
🌿 Other Off-label/Supportive Uses (Specialist-Guided)
- Intrapartum prophylaxis for Group B Streptococcus (GBS)
- Treatment of anthrax (Bacillus anthracis) infections, as part of combination therapy
- Empiric therapy for neonatal sepsis, often in combination with other antibiotics